CD70 antigen (CD70). Cytokine which is the ligand for CD27. The CD70-CD27 pathway plays an important role in the generation and maintenance of T cell immunity, in particular during antiviral responses.
NCT02830724 - Breast Cancer, Renal Cell Cancer, Ovarian Cancer, Pancreatic Cancer, Melanoma
The following plot describes the target topology, highlighting the
position of the endo-, ecto- and transmembrane domains, as well as the
position of a signal peptide, when present. The last three rows describe
the position of potential epitopes, as well as phosphorylation and
glycosylation sites.