Description

CD70 antigen (CD70). Cytokine which is the ligand for CD27. The CD70-CD27 pathway plays an important role in the generation and maintenance of T cell immunity, in particular during antiviral responses.


Clinical trials

NCT02830724 - Breast Cancer, Renal Cell Cancer, Ovarian Cancer, Pancreatic Cancer, Melanoma


Target gene expression

The following plot describes the expression, in different tissues and TCGA cancers, of the different isoforms of the gene CD70.


Target essentiality


Protein properties

The following plot describes the target topology, highlighting the position of the endo-, ecto- and transmembrane domains, as well as the position of a signal peptide, when present. The last three rows describe the position of potential epitopes, as well as phosphorylation and glycosylation sites.